Template:Streptococcal Pharyngitis Antibiotics

Revision as of 17:18, 28 January 2026 by Rossdonaldson1 (talk | contribs)

Treatment can be delayed for up to 9 days and still prevent major sequelae

Penicillin Options:

  • Penicillin V 250mg PO BID x 10d (child) or 500mg BID x 10d (adolescent or adult)[1]
  • Bicillin L-A <27 kg: 0.6 million units; ≥27 kg: 1.2 million units IM x 1 [1]
  • Amoxicillin 50 mg/kg once daily (maximum = 1000 mg) for 10 days[2]

Penicillin allergic (mild):[1]

  • Cefuroxime 10mg/kg PO QID x 10d (child) or 250mg PO BID x 4d
  • Cefixime 400mg/day PO in single daily dose x10d or divided q12hr x10d

Penicillin allergic (anaphylaxis):[1]

  • Clindamycin 7.5mg/kg PO QID x 10d (child) or 450mg PO TID x 10d OR
  • Azithromycin 12mg/kg QD (child) or 500mg on day 1; then 250mg on days 2-5
  1. 1.0 1.1 1.2 1.3 Shulman, et al. Clinical Practice Guideline for the Diagnosis and Management of Group A Streptococcal Pharyngitis: 2012 Update by the Infectious Diseases Society of America. Clinical Infectious Diseases 2012;55(10):1279–82
  2. CDC Website, accessed 2026-28-01. https://www.cdc.gov/group-a-strep/hcp/clinical-guidance/strep-throat.html