Loperamide toxicity

Background

• Increasing reports of intentional overdose at very high doses either for euphoric effects or to attenuate symptoms of opioid withdrawal

Clinical Features

• May have features of conventional opioid toxicity

Loperamide-induced cardiac toxicity

• Often young
• May present in cardiac arrest or with recurrent syncope in conjunction with ECG agnormalities

See Also

• Loperamide