Template:Sepsis Guidelines Steroids

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2012 Guidelines

Surviving Sepsis Campaign guidelines for severe sepsis and septic shock (2012)[1]

  • Do not use IV hydrocortisone to treat adult septic shock patients if adequate fluid resuscitation and vasopressor

therapy are able to restore hemodynamic stability. Otherwise intravenous hydrocortisone alone at a dose of 200 mg per day (grade 2C)

  • Do not use ACTH stimulation test to identify adults with septic shock who should receive hydrocortisone (grade 2B).
  • Tapering off hydrocortisone when vasopressors are no longer required is not needed (grade 2D).
  • Do not use corticosteroids for the treatment of sepsis in the absence of shock (grade 1D).
  • When hydrocortisone is given, use continuous flow (grade 2D)