Emergency contraception
Treatment
Progestin-Only Regimen
• First dose within 48 hours after unprotected intercourse followed by second dose 12 hours later
- may take both at once
• Relative risk redction of pregnancy = 89% (1% with vs 8% without)
• Side effects
(1) Nausea (23%)
(2) Vomiting (6%)
- no teratogenisis
• FDA approved regimens:
(1) Plan B (marketed specifically for emergency contraception) - 1 pill (0.75 mg levonorgestrel) per dose
Yuzpe Regimen
(combination OCPs)
• First dose within 72 hours after unprotected intercourse followed by second dose 12 hours later
• May be given up to 120 hours later (but efficacy reduced)
• Reduces risk of pregnancy by 75% (2% with vs 8% without)
• Side effects
(1) Nausea (50%)
(2) Vomiting (20%)
• Safety
(1) No teratogenic effect
• Contraindications
(1) Pregnancy
• FDA approved regimens:
(1) Ovral, Ogestrel - 2 pills (100 ug ethiny estradiol/0.5 mg levonorgestrel) per dose
(2) Alesse, Aviane, Levlite - 5 pills (100 ug ethiny estradiol/0.5 mg levonorgestrel) per dose
(3) Levlen, Levora, Lo/Ovral, Low-Ogestrel - 4 pills (120 ug ethiny estradiol/0.6 mg levonorgestrel) per dose
(4) Triphasil, Tri-Levlen, Trivora - 4 pills (120 ug ethiny estradiol/0.5 mg levonorgestrel) per dose
Source
7/09 PANI