Chikungunya

Background

Mosquito transmitted virus, originally found in West Africa but cases in the Americas beginning in 2013

Clinical Features

• Fever typically greater than 39deg
• Polyarthralgias, bilateral and symmetrical
• Rash- maculopapular
• Myalgias
• Nausea and vomiting
• Lymphocytopenia
• Elevated LFTs
• AKI
• 3-7d incubation period

Differential Diagnosis

Fever in traveler

• Normal causes of acute fever!
• Malaria
• Dengue
• Leptospirosis
• Typhoid fever
• Typhus
• Viral hemorrhagic fevers
  • Ebola virus disease
  • Marburg virus disease
  • Lassa fever
  • Crimean-Congo hemorrhagic fever
• Chikungunya
• Yellow fever
• Rift valley fever
• Q fever
• Amebiasis
• Zika virus
• Other infectious rashes

Workup

• CBC w diff, Cr, LFTs
• contact CDC for specialized testing; recommends tiger top tube

Management

Symptomatic treatment: acute symptoms usually resolve in 7-10d

See Also

• Travel Medicine

Sources

CDC