| Name
|
Presentation
|
Radiograph Findings
|
Clinical Importance
|
| Adamantinoma |
Bone pain over anterior tibia in adolescent or young adult |
Soap bubble osteolytic appearance on plain radiograph |
Metastasis to lungs; may need amputation
|
| Chordoma |
Constant pain if in sacrum; neurological deficits if at base of skull, most commonly in cranial nerves to the eye |
Plain radiograph will show a destructive bone lesion often with an associated soft tissue mass |
Slow growing but locally aggressive; metastasis is uncommon, local recurrence is much more likely
|
| Fibrosarcoma and Undifferentiated pleomorphic sarcoma |
Similar to osteosarcoma except malignant fibroblasts but less common |
Most common in distal femur and proximal tibia |
Similar outcome to osteosarcoma
|
| Primary bone lymphoma |
Adult > 40 years of age with bone pain or pathologic fracture |
Bone destruction; soft tissue mass |
5 year survival is greater than 50% with radiation and chemotherapy
|
