Diphenhydramine

General

  • Type: Antihistamines H1 blocker
  • Dosage Forms: Oral, IM, IV
  • Common Trade Names: Benadryl

Adult Dosing

  • Allergic Reaction
    • Oral: 25-50 mg q4-8h, max 300 mg/day
    • IM/IV: 10-50 mg/dose
  • Parkinsonian symptoms
    • Oral: 25-50 mg tid-qid
    • IM/IV: 10-50 mg/dose
  • Insomnia: 50 mg PO qhs

Pediatric Dosing

Special Populations

  • Pregnancy Rating:
  • Lactation:
  • Renal Dosing
    • Adult
    • Pediatric
  • Hepatic Dosing
    • Adult
    • Pediatric

Contraindications

  • Allergy to class/drug

Adverse Reactions

Serious

Common

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:
  • Mechanism of Action:

See Also

Sources

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