Hypoxemia

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Background

  • Defined as PaO2 <60 mm Hg
    • Amount of oxygen available is a function of the arterial oxygen content and blood flow
  • Occurs in states of low CO, low Hb, or low SaO2 (arterial oxygen saturation)
  • Relative Hypoxemia
    • PaO2 is < expected for given level of inhaled O2 (e.g. PaO2 of 100 on FiO2 100%)
    • Can calculate amount of relative hypoxemia by A-a gradient
      • P(A-a)O2 = 145 – PaCO2 – PaO2 (normal is <10 in young, healthy pts)

Pathophysiology

  • Hypoexemia results from any combination of 5 mechanisms
  1. Hypoventilation
    1. d

Work-Up

DDx

Treatment

Disposition

See Also

Source

Tintinalli

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