Hirudins
Revision as of 15:54, 22 March 2016 by Ostermayer (talk | contribs) (Text replacement - "Category:Drugs" to "Category:Pharmacology")
Background
- Direct thrombin inhibitors
Drugs
- Hirudin
- Lepirudin
- Argatroban
Indications
- HIT
- Unstable angina/NSTEMI/PCI
Complications
- Bleeding
- Majority of bleeding events occur at invasive sites
- No antidote available
- Minor bleeding
- Stop infusion
- Major bleeding
- Give FFP or PCC
Pharmacology
- Half-life is ~2hr