Neuroblastoma (peds)
Revision as of 10:06, 25 July 2016 by Neil.m.young (talk | contribs) (Text replacement - "==Diagnosis==" to "==Evaluation==")
Background
- Arises from primitive ganglion cells of sympathetic nervous system
- Most common neoplasm in 1st yr of life
- May arise anywhere along sympathetic nervous system
- Adrenal gland (40%)
- Abdomen (25%)
- Chest (15%)
Clinical Features
- Depends on location
- Large, painless abdominal mass
- Compression of bowel/bladder
- Horner syndrome
- Spinal cord compression
- Opsoclonus-myoclonus
- Highly associated with neuroblastoma
- Neutropenia/pancytopenia suggests bone marrow involvement
Differential Diagnosis
Evaluation
- CXR
Management
- Admssion for tumor biopsy